Developing viable and profitable new drugs today often requires working with new chemical entities (NCEs) that are poorly water soluble.
Challenging Drug Compounds
The Challenges and Opportunities for Healthcare Companies
Many of today’s NCE's require time-consuming experimentation and analysis in order to achieve satisfactory drug absorption from a solid oral dosage form – a challenge that can sometimes take years of development without yielding positive results. While at the same time, opportunities for unique OTC line extensions and generics abound.
The Capsugel Liquid-filled Advantage
Utilizing lipid-based technology, Capsugel developed proprietary systems designed to help you meet the challenges of formulating or re-formulating drugs in a liquid-filled format. Our approach offers significant benefits in quickly solving some of your most difficult drug development challenges including:
- Faster time-to-market through increased formulation and development speed and excipient reduction
- Improved bioavailability by promoting absorption for poorly soluble compounds
- Diminished inter-and-intra patient variability in absorption
- Diminished food effect
- Improved content uniformity, particularly at low dosage levels
- Solutions for high potency compounds, chemically unstable compounds and compounds with low melting points
- Turn-key manufacturing for ease of scale-up and validation
Not only does formulating in liquids help overcome obstacles once thought to be insurmountable, but it also can reduce development time. Time saved = more time selling under patent protection = increased revenue.
From initial discovery to full-scale commercial production, Capsugel has the global resources, knowledge, and talent to help you exceed your objectives.