The development of formulations is based on science, along with empirical habits and company practices. It is imperative that great emphasis be placed on the rationale used to derive the final drug along with a through and detailed documented process, especially with increased regulatory scrutiny.

To help address these requirements with formulating in hard gelatin capsules, a unique system known as the Expert System was created. This unique system developed under the authority of the School of Pharmacy at the University of London, with the support of the University of Kyoto, the University of Maryland and Capsugel sponsorship, captures the knowledge and experience of pharmaceutical experts from around the world.

The system collects input from users concerning drug properties, compatibility with excipients, capsule sizes and company practices and then puts this information into a complex but useful decision tree model based on the integration of three specialized databases. The output is a recommended formula and tests to be performed in a detailed report.

To learn more about the Expert System and how it can help your company, contact Capsugel at one of our worldwide locations.