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Protect the Potency and Improve Bioavailability of Liquid Products
It has long been known in the pharmaceutical community that liquid formulations can help protect potency and improve bioavailability. Now many nutritional supplement companies are taking their products to the next level by developing liquid-filled capsules. Consumers are specifically looking for liquid supplements and are often willing to pay a premium for them.
Licaps® liquid filled capsules offer significant dosage form advantages.
Less Oxygen Degradation
Hard gelatin Licaps capsules provide a significantly better barrier to the transmission of oxygen into the capsule than softgels, which can translate into improved potency protection.
Hard vs. Soft Gelatins - Oxygen Transmission Rate Comparison:
Improved Bioavailability
In a recent Human Dose Response Study, carried out by Accutest Research Laboratories Pvt. Ltd, comparative bioavailablility of four different preparations of Coenzyme Q-10 was analyzed in 24 healthy male volunteers, in fasting conditions.
The Licaps dosage form exhibited higher total absorption than the other dosage forms studied:
- Peak blood plasma levels were highest with Licaps capsules, and was 20% higher than softgels and 13% higher than effervescent tablets
- Total absorption* was highest in Licaps capsules, and was 47% higher than in softgel form and 44% higher than effervescent tablets

*AUC(0-∞ )
Capsugel's Complete End-to-End "Liquids" Offering
To help companies launch new liquids products, Capsugel offers a suite of products and services for liquid fills.
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